How to make DMT at Home easy steps

how to make dmt

How to make DMT at home, This potent psychedelic is surprisingly simple to create. The most straightforward technique is to extract it from DMT-containing plants, but it may also be made from commercially available materials with a basic grasp of chemistry and access to very basic laboratory equipment.

This article will go through three separate techniques for producing two types

We’ll go through the natural extraction method (beginning level), the Hamilton-Morris approach of synthesizing 5-MeO-DMT (intermediate level), and a way for creating (advanced level).

What is DMT?

DMT is an abbreviation for dimethyltryptamine, which is one of the simplest psychedelics in terms of molecular structure yet one of the deepest in terms of experience. There are several types of DMT, but the most popular are N, N, DMT, and 5-MeO-DMT.

It can also be inhaled or vaped, resulting in an intense but fleeting psychedelic experience.

DMT has been demonstrated in studies to dependably elicit mystical experiences that can help with dissolving deep psychological scars, addressing personal truths, and curing mental diseases. It is studied as a therapy for existential anxiety, depression, addiction, anxiety, migraine headaches, and a variety of other conditions.

How to Extract DMT From Plants

DMT is most easily produced by extracting it from plants. The most commonly utilized plant is Mimosa hostilis root bark, which is easily obtained online. Rather than 5-MeO-DMT or other hallucinogenic tryptamines, most plant sources include N, N, and DMT. Other sources, such as Acacia confusa, Psychotria viridis, and others, can also be employed.

The extraction may be carried out using basic ingredients purchased online or at large box retailers.


Plant material containing DMT — you can use Mimosa hostilis, Mimosa pudica, Psychotria viridis, or other DMT-carrying plants.

Naphtha is a nonpolar solvent.

Water that has been distilled

Lye (sodium hydroxide) how to make DMT at home

5% distilled white vinegar — muriatic acid can also be used


  1. Nitrile rubber gloves
  2. Goggles for safety
  3. Pipette or separation funnel—to extract the nonpolar layer containing the DMT (separate funnels also work well).
  4. Filters for coffee
  5. A few glass beakers or jars — never do these extractions in plastic or metal containers.
  6. A fridge with a freezer
  7. Blender or coffee grinder

The Process: Simplified

  1. Combine plant material, vinegar, and water.
  2. To raise the pH, add sodium hydroxide.
  3. To separate the DMT part, add naphtha.
  4. Refrigerate the solution to separate the DMT.
  5. Dry the freebase DMT powder after filtering it.

Step-By-Step Process for Extracting DMT From Plants

The fundamental technique of separating DMT from plant sources is straightforward and may be accomplished using easily available chemicals and without the requirement for a lab license. There are several chemical possibilities, and more complex techniques of purification, such as short-path vacuum distillation, can make the process more efficient but are not wholly essential.

The following procedure covers the most basic technique of DMT extraction that anybody may perform at home.

The most essential thing to note here is that, despite their accessibility, the chemicals employed in this procedure are extremely hazardous if handled incorrectly:

  1. Lye is caustic and can cause serious chemical burns to the eyes and skin if not properly protected with gloves and goggles.
  2. Because naphtha and other solvents are extremely flammable, keep the location well-ventilated and away from sparks or open fires.
  3. Some plants are hazardous; always get raw plant material from a reliable source to prevent extracting the wrong plant species.

The straightforward method for obtaining DMT from plants is as follows:

Step 1: Gently Heat the Plant Material in Water and vinegar

Begin by grinding the dried plant material into a fine powder in a blender or coffee grinder.

Then, gradually add 5% distilled white vinegar to the powdered herb (0.4 mL per gram of dry herb). Muriatic acid can also be used for this phase.

Add 3.6 mL of near-boiling distilled water (90) to 1 gram of dried root powder.

Warm the solution gently for about 3 hours, stirring often. You may accomplish this using a double boiler, hot plate, or slow cooker. Keep the heat on low; it should not be boiling.

Step 2: Strain to Remove the Plant Material

After about a half-hour, separate the plant material from the mixture using a cheesecloth or fine sieve. The liquid that remains is essentially a tincture of the original plant material. It will be quite black and smell strong.

Step 3: Basify The Solution

Mix around 5 g of lye (sodium hydroxide) with 100 mL of distilled water to basify the solution. Check the pH to ensure it is between 12 and 13. When the pH rises over 12, the hue changes from deep purple to dark black.

Gradually add the solution to the extraction; it will darken and begin to heat up. Allow the mixture to rest for 48 hours before proceeding to the next stage.

Step 4: Filter & Defat The Solution

The defatting method requires “washing” the solution with a nonpolar solvent, such as naphtha (available at camping stores as fuel or Zippo fluid).

After adding the solvent and stirring the mixture, a nonpolar phase will gradually begin to float to the top of the liquid. Allow the mixture to settle for 24 hours to thoroughly separate. Every few hours, softly shake the jar to combine the solution. If you shake too forcefully, the solution will emulsify and become much more difficult to separate.

DMT will diffuse from the bottom water layer to the top naphtha layer over a few hours.

Step 5: Separate the Top DMT-Containing Layer & Rechrystalize

Separate the clear top layer from the dark bottom layer with a pipette, turkey baster, or separating funnel. The DMT is located in the transparent top layer.

Put the solution in the refrigerator to chill. Chrystals will develop at the bottom of the solution, which is almost all freebase.

The mixture can then be filtered through a coffee filter to separate the DMT crystals from the naphtha. To remove the naphtha, let the coffee filters dry fully in a well-ventilated environment.

Step 6: Recrystallization & Further Purification

The substance you have at this stage can be smoked, but it’s a good idea to recrystallize it separately to purify the extract even more.

A tiny amount of naphtha is added to the powder and gently stirred until everything is dissolved. If it does not dissolve, you may need to gradually heat the solution in a double boiler. Be cautious here, since the naphtha will begin to evaporate at roughly 40oC. Never, ever use an open flame to heat the solution.

Place the solution in the refrigerator for a few hours, then in the freezer for a few more.

It is critical to allow the solution to cool gradually by chilling it to room temperature, fridge temperature, and finally freezer temperature — rather than going straight to the freezer. If you store the jar immediately in the freezer, you will not receive a good yield.

After a few hours, the DMT will create new crystals at the bottom of the jar that are purer than the initial set you made in step 4.

Using a coffee filter, remove the crystals from the naphtha. Spread the powder out on a dish and let it dry completely. Maintain adequate ventilation so that the naphtha may be safely removed when it evaporates from the powder.

How Pure is the Final Extract?

This approach is a proven way of manufacturing large amounts of DMT, although it will never be entirely pure without further lab purification processes.

Other components in the plant will be isolated using the same method. The chemicals extracted are determined by the source of the raw plant material, the solvents utilized, and other considerations. how to make DMT at home

Where Can I Buy DMT-Containing Plants?

DMT itself is illegal everywhere, but the plants that contain DMT aren’t regulated as such. Banning DMT-containing plants would be difficult because there are so many of them. A lot of DMT-containing plants are classified as weeds as it is, so banning them would be virtually impossible anyway.

The most common plants used to extract DMT are Mimosa hostilisPsychotria viridis, and Acacia confusa — both are legal throughout the world, grow abundantly in warm climates, and can be purchased in bulk online. If you are a DMT lover you can click on the like for 4 aco dmt for sale and 5 meo dmt for sale

Plant Sources of DMT

  • Aerial portions of Psychotria viridis contain 0.44% N,N, DMT.
  • Desmanthus illinoensis root bark contains 0.34% N, N, and DMT.
  • Pilocarpus organensis contains 1.06% 5-MeO-DMT.
  • N,N,DMT, 0.02% Phalaris tuberosa — 0.10$
  • Phalaris arundinacea contains 0.060% N,N,DMT.

How to Synthesize 5-MeO-DMT

Synthesizing 5-MeO-DMT is more difficult than extracting it from plants and necessitates more sophisticated laboratory equipment. Having said that, it’s still a reasonably straightforward procedure that anybody with a basic grasp of chemistry and lab skills can conduct safely and successfully.

Hamilton Morris made a video in 2021 that effectively showcases a modified version of the EschweilerClarke reaction that uses 5-methoxy-tryptamine as the starting ingredient (which is currently legal and commercially accessible).

The reaction is quite straightforward, including a full transformation with only one reaction.

After synthesis, the 5-MeO-DMT is purified, purified again, and tested.


  1. 5-Methoxy-Tryptamine
  2. Methanol
  3. Potassium Hydroxide
  4. Formaldehyde
  5. Sodium cyanoborohydride


  1. Condenser for Reflux
  2. Chamber of Reaction
  3. Evaporator Rotating
  4. Thermometer
  5. There are two extra funnels.

The Process: Simplified

  1. Mix 5-methoxy-tryptamine, formaldehyde, and sodium cyanoborohydride slowly.
  2. Skim the 5-MeO-DMT that floats to the surface.
  3. Distillation and recrystallization are used to purify.
  4. The final sample should be tested.

Step-By-Step Process:

Finding a supply of raw 5-MeO-tryptamine freebase – a completely legal substance accessible from chemical merchants or wholesalers — is the simplest approach to producing 5-MeO-DMT. The cost of these items varies greatly depending on where you reside.

Step 1: Dissolve the 5-methoxy-tryptamine free base in methanol

To aid the process, dissolve the powdered 5-MeO-tryptamine in methanol or a similar solvent. This substance is widely available (legally), and it is most typically utilized in the production of melatonin. To form 5-MeO-DMT, this molecule must undergo a straightforward reduction process.

Step 2: Bring the mixture to room temperature.

The reaction vessel and the 5-MeO-tryptamine are chilled to 0oC using an ice bath or chiller.

Step 3: Slowly Combine Formaldehyde and Sodium cyanoborohydride

Slowly pour the reducing chemicals into the reaction vessel using two extra funnels. These ingredients should be added slowly while swirling continually.

Step 4: Vacuum the Methanol

Warm the mixture gently overnight to evaporate the methanol. As the methanol evaporates, 5-MeO-DMT “oil slicks” appear on the liquid’s surface.

Step 5: Purify the 5-MeO-DMT

Now that the 5-MeO-DMT has been formed, it must be separated from the other components in the mixture. Short-path vacuum distillation concentrates the crude DMT freebase while distillation eliminates the water. The next step is to recrystallize the 5-MeO-DMT by dissolving it in warm methanol and then chilling it for a few hours to form crystals on the bottom of the container.

After that, the mixture is filtered, dried, and tested for purity. Slowly pour the reducing chemicals into the reaction vessel using two extra funnels. These ingredients should be added slowly while swirling continually.

Step 4: Vacuum the Methanol

Warm the mixture gently overnight to evaporate the methanol. 5-MeO-DMT “oil slicks” emerge on the surface of the methanol as it evaporates.

How to Synthesize N, N, DMT

The most difficult of the three ways, synthesizing N, N, and DMT, takes a far greater level of ability and experience to accomplish safely and efficiently.

Furthermore, the chemicals required to conduct the extraction are more difficult to get and are extremely combustible, corrosive, and poisonous. how to make DMT at home


  1. Oxalyl chloride
  2. Diethyl ether
  3. Lithium aluminum hydride
  4. Ether
  5. Distilled water
  6. Tetrahydrofuran

The Process: Simplified

  1. Tryptamine should be dissolved with Diethyl Ether.
  2. N, N, DMT is formed by reacting with reagents.
  3. Make the DMT Salt
  4. Recrystallize and discard any solvents
  5. Final Product Testing

Step-By-Step Instructions for Synthesizing DMT

Alexander Shulgin described the following approach in his book PIHKAL. To be performed properly, this technique needs some lab experience as well as access to many pieces of lab equipment.

Step 1: Dissolve Tryptamine With Diethyl Ether

The first step is to dissolve tryptamine, the precursor for N, N, DMT, in diethyl ether. Stir it for a few minutes to ensure that all of the tryptamine is dissolved.

Step 2: Mix the Tryptamine Solution with the Oxalyl Chloride.

Add the oxalyl chloride as a reagent to generate indole oxalyl chloride, which works as an intermediate between the beginning material (tryptamine) and the end product (N, N, DMT). This reaction produces a yellow crystalline material that settles to the bottom of the container.

The indole oxalyl chloride is then reacted with a molecule known as dimethylamine. This results in the following chemical intermediate, indol-3-yl-N,N-dimethyloxylamide.

For several minutes, stir the solution until a white precipitate appears at the bottom of the container.

Remove the White Substance from the Liquid in Step 4

Remove the white stuff from the container by filtering the entire mixture. Allow it to dry in a well-ventilated location after washing it with ether and water to remove all of the diethyl ether.

Step 5: Mix in the Lithium Aluminum Hydride.

Make a tetrahydrofuran solution of lithium aluminum hydride and add the white powder from step 4.

Allow the entire solution to cool to room temperature after many hours of refluxing. To remove any excess hydroxide left over from the process, add some dioxane. The resultant combination should produce a white sediment at the bottom of the reaction jar, including the DMT as well as various contaminants that must be removed.

6th Step: Filter, Wash, and Dry

Remove the white DMT-containing powder by filtering the mixture. Rinse it many times with tetrahydrofuran before drying it with anhydrous magnesium sulfate.

Recrystallize the impure powder in step 7.

The powder you’re left with now has a high concentration of DMT, but it’s not pure. It must be cleansed before it can be used.

In a solvent such as petroleum ether, dissolve the powder and gradually heat the solution until the powder is entirely dissolved. Allow the solution to cool to room temperature before forming DMT crystals. To remove the DMT from the solution, you may need to put it in the fridge.

Allow the powder to air-dry in a well-ventilated area after filtering it. At this stage, you still don’t have pure DMT.

Step 8: Produce DMT Salt

Combine the powder with anhydrous diethyl ether and anhydrous hydrogen chloride. The end product of this reaction is N, N, DMT hydrochloride. It’s a DMT salt that will remain stable over time. Allow the powder to dry after filtering.

Step 9: Recrystallize again.

While slowly heating, add the powder to methanol or benzene. When all of the powder has been dissolved, remove from heat and set aside to cool. DMT hydrochloride will begin to crystallize gradually in the container, which may then be filtered and air-dried one last time.

The end result is almost pure N,N,dimethyltryptamine hydrochloride.

IMPORTANT: Laboratory Safety

Making DMT isn’t difficult, but it does require the use of very combustible and poisonous materials. It is vital that anybody attempting to create this material understands the hazards and how to reduce the degree of risk involved.

Even in a well-equipped laboratory, errors can (and often do) result in explosions, fires, and even deadly exposure to dangerous substances.

Here are some crucial things to remember when working in a lab:

  1. Always put on gloves and safety goggles.

Many of the chemicals used in the extraction or synthesis of DMT are caustic (causes chemical burns), poisonous, or flammable – all three are perfectly reasonable reasons to wear protective clothing to avoid inadvertent damage.

While you may believe these precautions are unnecessary since you’ve “never had an incident before,” this is a logical fallacy you don’t want to discover the hard way. Just because you haven’t had any problems in the past doesn’t guarantee it won’t happen again.

Any of these compounds can cause lifelong damage if they get into your lungs, skin, or eyes.

  1. Check for Adequate Ventilation

Naphtha and other solvents are very combustible. Heating these substances causes them to evaporate into the air, which is one of the stages. If there is insufficient airflow to remove these chemicals as they evaporate, they may be ingested (toxic) or come into contact with a spark or flame, causing an explosion and subsequent fire.

It’s better to execute these reactions in a workshop equipped with HVAC systems, or at the absolute least with the garage door open and a fan moving air from within the garage to the outside.

Know the Chemicals You’re Using

Some of the ingredients listed in the recipe lists above may be found in over-the-counter cleaning products such as Draino. These cleaning products, however, are not pure. Other additions may be hazardous or result in the formation of unknown dangerous byproducts.

When feasible, utilize lab-grade chemicals and make sure you understand the procedure before you begin.

  1. Never use an open flame to heat your solvents.

Similarly to point number two, if any of the solvents that evaporate into the air come into contact with an open flame or spark (including static electricity), they might start a fire. Before you begin, make sure there are no open flames (such as a heater or burner), that you do not smoke, and that you do not use your

  1. Put Your Final Product to the Test Before You Use It

Even the world’s top chemists examine the finished product to ensure its purity. While most people undertaking DIY extractions in their garage won’t have access to a mass spectrometry machine, there are alternative, less sophisticated techniques of assuring the end products are what they think they are. how to make DMT at home

When you’re finished, order some reagent harm-reduction kits to test a sample of your product. This will not establish the purity of the finished product, but it will guarantee that you did not utterly miss the mark and wind up with something quite different.

The Chemical Structure of DMT

DMT is classed as an indole alkaloid, as are many other hallucinogenic substances, including LSD (lysergic acid diethylamide) and psilocybin (magic mushrooms). It also serves as the foundation for the amino acid tryptamine, as well as serotonin and melatonin.

Over 4,000 distinct indole alkaloids exist, with many of them being pharmacologically active in humans.

All indole alkaloids have a 6-sided benzene ring joined to a 5-sided pyrrole ring as their basic structure.

The DMT molecule is one of the most basic psychedelics known. It has a slightly larger molecular weight than glucose. Because of its tiny size, it crosses the blood-brain barrier significantly more easily than other psychedelics.

The History of DMT Production

The earliest type of DMT extraction is ayahuasca, which is found in the Amazon. The ayahuasca brew is simply a water extract containing DMT extracted from local plant species, as well as a sequence of harmala alkaloids extracted from the ayahuasca vine (Banisteriopsis caapi).

The Canadian scientist Richard Helmuth Frederick Manske synthesized N, N, DMT for the first time in a lab in 1931. Manske had no notion the chemical he produced had hallucinogenic properties at the time.

Later, in 1946, Oswaldo Gonçalves de Lima, a Brazilian scientist, extracted N, N, DMT from the bark of Mimosa hostilis.

There have been hundreds of papers showcasing novel approaches or breakthroughs in the manufacture and extraction of synthetic DMT.

The Second Wave…

Isolated DMT was originally produced less than a century ago, in 1931, by Canadian scientist Richard Manske. In 1946, scientist Oswaldo Gonçalves de Lima found the chemical in plants.

But it wasn’t until 1956 that Hungarian chemist Stephen Szára discovered DMT’s secret hallucinogenic and psychedelic properties (by injecting himself and other volunteers with it…whew). This is when DMT emerged, not just as a counter-culture party drug and consciousness exploration tool, but also as a topic of intense scientific study, particularly among academics in the field of mental illness. (An unproven idea held that schizophrenia was caused by a metabolic mistake that created similar hallucinogens in the human brain, resulting in a schizo- or psycho-toxin.)

Large-Scale DMT Production

The methods described above are the simplest ways to produce DMT, although they aren’t always the most efficient on a big scale.

A late-2020 publication does an excellent job of detailing the procedures utilized to synthesize 5-MeO-DMT at scale. Rather than focusing on cost-cutting or simplicity, these strategies optimize the potency and consistency of output from batch to batch.

This paper described three ways to produce 5-MeO-DMT from various starting materials:

1. Modified Eschweiler−Clarke Reaction

  • Single-step reaction
  • Simple process
  • Difficult to scale

The methods described above are the simplest ways to produce DMT, although they aren’t always the most efficient on a big scale.

A late-2020 publication does an excellent job of detailing the procedures utilized to synthesize 5-MeO-DMT at scale. Rather than focusing on cost-cutting or simplicity, these strategies optimize the potency and consistency of output from batch to batch.

This paper described three ways to produce 5-MeO-DMT from various starting materials:

2. The Speeter−Anthony Tryptamine Synthesis

  • 90% efficiency in conversion
  • Scaling is difficult.
  • Ingredients that are sensitive to oxygen are required.

This is the most commonly quoted process in academic literature. It’s utilized to create hallucinogenic tryptamines like psilocybin and psilocin. Because it is simpler to scale, this technique is being phased out in favor of the Fischer indole reaction.

3. The Fischer Indole Reaction

  • 80% efficiency in conversion
  • One-step procedure
  • There will be no high temperatures.
  • This occurs in an aqueous solution.
  • It is suitable for both 4-MeO-DMT and N, N, DMT.

This process is thought to be the best for large-scale production because it is scaleable, has only one reaction step, does not require high temperatures (which is less dangerous), occurs in an aqueous solvent, does not require the use of air-sensitive or pyrophoric reactants, and uses simple, readily available ingredients.

How to Use DMT

The DMT produced by the procedures outlined above is a fine, white-to-brownish powder. The following is how to utilize freebase DMT powder:

1. Vape It

The most basic way to use DMT is to vaporize it. There are two primary approaches to this:

Make a DMT-charged E-liquid by dissolving the powder in an E-liquid base (which is widely accessible online), then filling an E-liquid vape pen with the DMT-charged E-juice. The juice may be made as strong as you like, but the most usual ratio is 1:1. This implies that for every 1 mL of E-liquid, you need to add around 1 gram of DMT powder.

Use a mesh or mod vape pen to vape raw DMT powder. These devices include a stainless steel mesh that keeps the powder above the heating element. This is the finest way to achieve a single-hit breakthrough.

DMT may be smoked in a bong or pipe. It will be quite harsh regardless of how you smoke it. Some individuals like to smoke DMT using crack pipes because they can regulate the temperature better than putting the flame straight on it.

2. Smoke It

Never use DMT powder without properly weighing it. This material is quite powerful.

3. Eat It

Nothing happens if you consume DMT powder straight. To act, it must first be used with a monoamine oxidase inhibitor.

This is a delicate business that should not be attempted without proper understanding and supervision from experienced users. MAO inhibitors are classified into two types: herbal MAO inhibitors and pharmaceutical MAO inhibitors.

Pharmahuasca is the most often used preparation for this. The approach uses synthetic substances to replicate ayahuasca. This entails combining DMT with a prescription MAO inhibitor such as isocarboxazid (Marplan). This combination is risky since Marplan is a strong medication with a broad list of potential adverse effects.

Syrian Rue and Ayahuasca vine are two herbal possibilities. They may be used with DMT to make a very potent tea. The experience with this approach will range from being completely psychoactive to being quite psychoactive.

Final Thoughts: On How to make DMT at home

Making DMT is simpler than you would think. It can be extracted and concentrated from plants, but it can also be produced using relatively basic chemistry.

A single lab could theoretically create enough DMT to feed the entire continent. Processes that manufacture 5-MeO-DMT and N, N, DMT with an efficiency of more than 80% are currently being investigated. how to make DMT at home

It is critical that we set the benchmark for DMT production early on before it spirals out of hand. When narcotics become popular, all kinds of immoral players join the market, according to history. These manufacturers may not have as much control over their manufacturing processes as we require. As a result, potentially hazardous, contaminated, or low-quality DMT might reach the market.

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