Synthetic mushrooms, or 4-AcO-DMT, are a prodrug of a psychoactive substance found in magic mushrooms (psilocin). 4 aco dmt dosage, buy 4-aco-dmt usa
Aside from a few small subjective differences, the experience is almost exactly the same as the effects of magic mushrooms.
The patents for this tried-and-true compound have been gone for decades, which is bad news for companies like Compass Pathways that are trying to corner the market for synthetic psilocybin for the next 20 years.
Here is all the information you need to know about 4-AcO-DMT.
What is 4-AcO-DMT?
The name for 4-Acetoxy-DMT is 4-AcO-DMT. It was made by Albert Hofmann and Franz Troxler. Hofmann is the same person who made LSD (lysergic acid diethylamide). It was made by two people in the early 1960s as part of their research into what made psychedelic mushrooms work.
4-AcO-DMT is a chemical that is made from psilocin, which is the main drug in magic mushrooms. The liver changes both psilocybin and 4-AcO-DMT into psilocin, which is then what makes you feel high.
Because of this, 4-AcO-DMT has almost the same effects as psilocybin or psilocin.
Sandoz, the company where the team worked, filed for a patent in January 1963, but they never got to use it to make money. They didn’t know what to do with this or any of Hofmann’s drugs that made people feel different (including LSD and psilocybin).
All of this happened right after the Timothy Leary and Richard Alpert-led Harvard Psilocybin project. Sandoz gave Leary a lot of LSD so that he could study it and try to find ways to make money with it in the field of psychotherapy.
4-AcO-DMT was put away for many years until a man named David E. Nichols started pushing for it to be used in psychedelic-assisted psychotherapy in the late 1990s. He wanted to get scientists to look more closely at this compound so that it could be used in medicine in the future. Nichols liked it because it always worked, was cheap, and had a lot of power.
There hasn’t been a single clinical study on the effects of 4-AcO-DMT, which is a shame. Most of the information we have now comes from studies on animals and personal stories.
Even though this drug hasn’t been studied much, 4-AcO-DMT is one of the most popular synthetic psychedelics. It’s not as popular as LSD or ketamine, but it’s more popular than 2C-B, Dipt, and other drugs in the 2C-X family.
In its raw form, 4-AcO-DMT is a brownish-white powder that is usually sold in capsules or tablets.
4-AcO-DMT: Specs & Technical Details
|Level of Risk||Low|
|Other Names||Synthetic Shrooms, Psilacetin, 4-acetoxy-DMT, or 4-AcO-DMT|
|Most Common Side-Effects||Anxiety & Paranoia|
|Duration of Effects||2–6 hours|
|Legality||Illegal in most countries, legal in Canada|
What Does 4-AcO-DMT Feel Like?
In general, 4-AcO-DMT is similar to how psilocybin mushrooms make you feel. The active ingredient is not 4-AcO-DMT itself, but psilocin, which is made from it. This means that 4-AcO-DMT is a precursor to the psychedelic substance psilocin, which is found in nature.
At lower doses (up to 30 mg), it’s hard to tell the difference between 4-AcO-DMT and magic mushrooms. It makes people hear and see things that aren’t there, improves self-reflection and existential thinking, shuts down the default mode network (DMN), and changes how time and sensory information are perceived. 4 aco dmt dosage
When you take more than 30 mg of 4-AcO-DMT, the effects start to change. This dose is very strong and looks a lot more like DMT. The images become much more fractal and geometric, and the hallucinations, feelings of empathy, and the ability to think deeply about things get very strong.
One of the main reasons why so many people only use this drug once is because of its existential weight of it, especially in higher doses. It’s not clear why high doses of 4-AcO-DMT are more likely to cause scary or uncomfortable trips than high doses of magic mushrooms.
Through our trip surveys, 11 people have told us that they used 4-AcO-DMT. Most people took between 20 and 30 mg, and the effects were said to be similar to those of magic mushrooms, but a bit less intense.
Common Reported Effects from 4-AcO-DMT:
- Altered perception of time
- Fractal geometric patterns
- The perception of music changes, sometimes for worse, sometimes for better
- Full-body floating sensation
How Long Does 4-AcO-DMT Last?
The effects of 4-AcO-DMT and shrooms don’t last as long as those of shrooms. This thing can last between 2 and 6 hours. It only lasts for 8 hours once in a very long time, like magic mushrooms.
If you take 4-AcO-DMT on an empty stomach or snort the powder instead of taking it as a capsule, the effects will start and end more quickly.
For instance, if you take 4-AcO-DMT in the form of a capsule, it could take up to 45 minutes for it to start working. Around the 2-hour mark, the best part of the experience starts, and over the next 2–4 hours, it slowly gets worse.
If you inhale (snort) the powder, the effects start about 15 minutes later, reach their peak after an hour, and start to wear off over the next two or three hours.
What’s the Dose of 4-AcO-DMT?
One of the best things about 4-AcO-DMT, and a reason why people like David Nicoles support it so much, is that it always has the same effects.
Since this is a pure compound with a fast and predictable metabolism, it is much easier to judge how strong the effects are than with psychedelics that are more natural. Plants and fungi are more difficult to dose because the number of active ingredients in each sample can vary a lot.
Most people take between 10 and 30 mg of 4-AcO-DMT. Some people take less (microdose) and others take more (heroic dose). Subjectively, a 20 mg dose is about the same as 3 grams of dried psilocybin mushrooms.
If you’ve never used 4-AcO-DMT before, it’s best to start with a small amount and slowly increase it over time.
The dose of 4-AcO-DMT is slightly different depending on the type. For example, you need about 1.24 mg of powder if you use 4-AcO-DMT fumarate salt. If you want to use 4-AcO-DMT hydrochloride salt, you only need 1.15 mg of powder. If you inhale the active ingredients instead of taking them by mouth, the dose is also about 20% lower.
Here’s some general dosage information to get you started:
- Microdose — 1–2 mg
- Threshold Dose — 5 mg
- Light Dose — 10 – 20 mg
- Standard Dose — 20–30 mg
- Heroic Dose — 40+ mg
How Does 4-AcO-DMT Compare With Other Psychedelics?
4-AcO-DMT is most like psilocybin and psilocin, but it is also like LSD, N, N, DMT, and 5-MeO-DMT, which are also indole alkaloids. It’s the same as research chemicals like 4-AcO-MET, 4-AcO-DET, 4-AcO-MiPT, and 4-AcO-DiPT, which can make people feel high. 4 aco dmt dosage
4-AcO-DMT vs. Psilocybin
Synthetic shrooms are what most people call the drug 4-AcO-DMT. This is because once 4-AcO-DMT is in the body, it is broken down in the same way as the active ingredients in magic mushrooms. It gets changed into psilocin, which then interacts with 5-HT2A receptors in the brain to cause the psychedelic state.
4-AcO-DMT is similar to psilocin (4-PO-DMT) and psilocybin (4-AcO-DMT) (4-HO-DMT). There are more similarities between these drugs than differences, and most people won’t be able to tell the difference between taking 4-AcO-DMT and taking magic mushrooms or even synthetic psilocybin.
There are, however, a few small differences between these things.
For example, when used in lower doses, 4-AcO-DMT is less intense than magic mushrooms. It’s calmer, more thoughtful, and sharper. Most of the time, magic mushrooms make people feel fuzzy. It can be hard to decide what to do, and your vision may feel blurry. This effect isn’t as strong when you use 4-AcO-DMT.
The times they start are also different. The effects of 4-AcO-DMT happen pretty quickly, especially if you take it on an empty stomach or inhale it. It can take an hour or more for magic mushrooms to start to work, but 4-AcO-DMT usually starts to work in 30 to 45 minutes.
4-AcO-DMT is also less likely to make you feel sick, which is a common side effect of magic mushrooms. The most likely reason for this is that 4-AcO-DMT doesn’t have any of the chitin or fibers that can irritate the digestive lining and are found in magic mushrooms.
When taken in larger amounts, 4-AcO-DMT starts to be different from magic mushrooms. If you take more than 40 mg, the effects are more like DMT. Even more than high doses of magic mushrooms, it causes powerful fractal and geometric hallucinations and deep existential “realizations.”
4-AcO-DMT vs. 5-MeO-DMT
Both 4-AcO-DMT and 5-MeO-DMT are made of the same psychedelic chemical made by the Bufo alvarius toad.
Even though the effects are similar (both compounds activate the 5-HT2A receptors), the effects are very different in terms of how strong they are.
The psychedelic effects of synthetic shrooms are similar to those of magic mushrooms, LSD, 2-CB, and LSA. It can change how we see time and space, how we understand what our senses are telling us, and how open our minds are to entropy. People think that higher entropy plays a role in mystical experiences and the existential realizations that come with them.
On the other hand, 5-MeO-DMT is a whole different thing. The experience is so deep that it’s almost impossible to put into words. Users often feel like they are completely out of their bodies and lose touch with reality and life as they know it.
The length of time is the other big difference. 5-MeO-DMT usually lasts between 15 and 30 minutes, but 4-AcO-DMT usually lasts between 2 and 6 hours.
4-AcO-DMT vs. LSD
The effects of 4-AcO-DMT and LSD or similar drugs are similar, but they are also different in some ways.
LSD is more likely to make you see things and clear your mind, while 4-AcO-DMT is more likely to give you a body high and make you feel “more grounded.”
Both compounds try to bind to the same receptors, but they do so in different ways. The 5HT2A receptors are the main target because they are what cause most of the psychedelic effects.
In online shops, you can often find 4-AcO-DMT next to a chemical called 1P-LSD (especially in Canada where both compounds are legal).
In the same way that 4-AcO-DMT is the prodrug for psilocybin, 1P-LSD is the prodrug for LSD.
PRO-LAD, AL-LAD, LSZ, ETH-LAD, and ALD-52 are all derivatives of LSD that are similar to these drugs.
Is 4-AcO-DMT Safe?
The safety profile of 4-AcO-DMT is very good. In the last ten years, a lot of people have been interested in it. Yet, there have never been any major safety concerns about how it has been used.
Like most indole alkaloids (psilocybin, psilocin, LSD, DMT, LSA), even when taken in high doses, there aren’t many bad effects on the body. liberty cap
All of these substances have been tested thoroughly to find out how safe they are. No one who only used 4-AcO-DMT has ever been said to have died. Some people have died because of other drugs. 4 aco dmt dosage
As with any psychedelic drug, there is a chance that using this drug could hurt your mind. It’s possible that taking 4-AcO-DMT could make psychotic breaks worse or cause them.
Powerful psychedelic experiences can also cause an ontological shock if the person wasn’t ready or didn’t have the tools to make sense of what happened. This can cause long-term mental problems like post-traumatic stress disorder (PTSD), depression, and anxiety.
The main safety concerns with this substance are the dose (it’s easy to take too much) and tampering with fentanyl, PCP, or NBOMe, which could make it more dangerous. Since it’s a chemical powder, it’s much easier to mix it with chemicals that are bad for you. Before you think your 4-ACO-DMT is pure, you should always test it.
You should always use a drug testing kit to check what you are taking. When I do this, I like to use kits from Elevation Chemicals.
How to Drug Test 4-AcO-DMT
A key part of using substances safely is testing them with a reagent test kit. This is especially true when working with powders or liquids. Basically, you should always test anything that isn’t a raw plant or fungus to make sure you’re using what you think you’re using.
Please keep in mind that reagent testing only tells you what kinds of compounds are in a sample, not how pure it is. This is done to reduce the risk of harm, but it doesn’t prove that the sample you’re using is safe.
You only need a small amount of your substance to test it, and the reagents are very inexpensive. For each test, you only need a drop and a sample about the size of a grain of sand. Testing is cheap, quick, and good at making sure things are safe.
With that aside, here’s how to test 4-AcO-DMT:
In an ideal world, you would use the Ehrlich, Marquis, Mecke, and Mandelin reagents to run four tests. Each one looks for a different kind of chemical.
If you don’t have a lot of money, the most important test would be the Ehrlich reagent, which looks for indole alkaloids. If this test doesn’t work, meaning it doesn’t turn purple, the substance you have is not 4-AcO-DMT, and you should stay away from it at all costs. Penis envy mushroom
To run the test, take a small sample and put it on a white ceramic or plastic surface. The size of the sample should be about the same as a grain of salt. Next, put one drop of the test reagent on the sample and watch how long it takes to change color. Wait 3 minutes to see what color the mixture is after the reaction is done.
Here’s what to expect if your sample is 4-AcO-DMT using the four test reagents noted above:
- Ehrlich — Used to detect indole alkaloids. It should turn purple within 2 minutes.
- Marquis — Used to detect amphetamines. Should not change color.
- Mecke — Used to detect the presence of opioids. Light green or blue color indicates the presence of opiates. May turn a dark green color.
- Mandelin — Used to differentiate some alkaloids. Should remain yellow, or turn a darkish green (not red, black, or orange)
Side Effects of 4-AcO-DMT
When 4-AcO is highly concentrated, it is very powerful. You only need a few mg of powder to get a strong dose, while you need several grams of mushrooms to get the right dose. Even if you take a few milligrams more than you should, the effects won’t change much. Even a few mg more of 4-AcO-DMT can make a big difference in how it makes you feel.
Large doses of 4-AcO-DMT tend to make the trip harder than low doses, which tend to be calm and positive.
Even so, 4-AcO-DMT rarely makes people feel bad in other ways. Here are some of the side effects of 4-AcO-DMT that people told us about in our trip surveys, along with my own experiences.
Potential side effects of 4-AcO-DMT Include:
- Nausea & vomiting
- Heart palpitations
- Flushing in the face and chest
Is 4-AcO-DMT Legal?
Most places around the world don’t have clear laws about 4-AcO-DMT. Regulators haven’t paid much attention to it, and it’s not on any lists of banned substances in the US, Canada, or the UN Convention on Psychotropic Substances. 4 aco dmt dosage
This chemical is technically legal in Canada, and there are many places online where you can get it.
Things are a little different in the United States. Even though it is not called psilocin, 4-AcO-DMT is similar to it. Psilocin is a drug that is illegal. Under the Federal Analogue Act, 4-AcO-DMT is technically a Schedule I drug, but it’s very unlikely that someone would be arrested for having this substance. polkadot chocolate
Under the Misuse of Drugs Act of 1971, 4-AcO-DMT is a Class A drug in the UK.
In Australia, 4-AcO-DMT is on Schedule 9, which means it can only be sold legally if the government gives the seller permission. We haven’t been able to find any legal sources of 4-AcO-DMT in Australia, and it looks like they aren’t giving out licenses for this substance.
How 4-AcO-DMT Works
4-AcO acts on the 5-HT2A serotonin receptors, just like most indole psychedelic alkaloids. The default mode network (DMN) in the brain is thought to be turned off by these receptors.
This network is in charge of making sure that other parts of the brain can talk to each other. It acts like a valve that limits the amount of information that gets into the brain and stops certain things from happening in the brain. The goal of this system is to make us more productive and stop us from getting too busy over small things.
When psychedelics like 4-AcO-DMT are used to shut down the DMN, this reducing valve is left wide open. This makes it possible for the brain to be much more active in response to thoughts about the self and sensory information.
This state makes us more creative and better at thinking outside the box. It also changes how we understand the time and sensory information and brings up memories and feelings that are normally buried in the brain. This leads to visual and auditory hallucinations, a deep state of introspection, ego death, and dissolution, and a strong feeling of being connected to the world around us.
Most indole and phenethylamine psychedelics have the same effect. All of these chemicals work by affecting the same receptors, but they all have different effects on other serotonin receptors, NMDA receptors, GABA receptors, and a lot more. This is what makes the effects of psychedelics so different, even though they all do the same thing in the end.
Frequently Asked Questions About 4-AcO-DMT
Even though 4-AcO-DMT has been around since the 1960s, there is still a lot we don’t know about it. So far, there hasn’t been any good clinical research on this compound and how it might be used in psychotherapy or to treat conditions like cluster headaches or anxiety. Psilocybin has already shown a lot of promise in both of these areas.
Here are some of the most common practical questions we get about using 4-AcO-DMT, though:
1. What Color Should 4-AcO-DMT Be?
There are two main types of 4-AcO-DMT, and each has a slightly different color.
4-AcO-DMT hydrochloride is a light brown powder with a whitish color. Sometimes the powder is very fine, like flour, and sometimes you can see crystals forming.
4-AcO-DMT fumarate salt also has a whitish-brown color but is usually a little darker than the hydrochloride salt version.
Color alone is not a reliable way to assess purity. You’ll need to use a reagent test kit for this. If you find powders that are very dark brown, black, or pure white, you should be extra skeptical and make sure you test the substance before you use it.
2. Can I Make 4-AcO-DMT at Home?
Technically, you can make 4-AcO-DMT with some fairly common lab equipment and chemicals, but it’s strongly advised that you don’t try this at home.
Synthesizing 4-AcO-DMT and related compounds isn’t too hard, but there’s a lot of room for error in the reaction, which could lead to potentially harmful byproducts. It’s also highly illegal in most countries.
So, if you’re interested in this topic, you can look up how to make 4-AcO-DMT.
3. Where Can I Buy 4-AcO-DMT?
You’re out of luck if you live in the United States. This compound is against the law in the US, so there is no legal way to get it. You can buy it from street vendors, which is illegal, but there is a high chance that the products have been tampered with. We suggest that you don’t order 4-AcO-DMT or any other illegal substance. Shroom price
You can legally buy this compound from places like ChemLogix if you live in Canada. It’s actually very cheap, with four standard doses costing about $25 CAD (25 mg each)
The Future of 4-ACO-DMT
4-AcO-DMT has been around for a long time, but until about ten years ago, no one knew anything about it. Since then, people have become more interested in this substance, and it is now one of the most common synthetic psychedelics on the market. polka dot chocolate NYC
We think that people will become more interested in 4-AcO-DMT over the next few years. Several companies are already making their own synthetic versions of psilocin or psilocybin, but most of them want to patent the final product. This will give them the chance to raise the price of the product and control how it is sold.
4-AcO-DMT is no longer protected by a patent and is now in the public domain. This means that the compound will always be cheap, even if psychedelics become legal and more companies start selling it.
This psychedelic is easy to make and doesn’t cost much. It has all the same effects and benefits as magic mushrooms, and the dosage is more consistent. The effects of 20 mg of 4-AcO-DMT are always the same. However, repeated doses of magic mushrooms can have a wide range of effects depending on which mushroom is used. This means that the effects of 4-AcO-DMT are much more predictable, which makes it a better choice for psychedelic-assisted psychotherapy.